Consider the following propositions for rephrasing the segment It may not matter directly for everyday life, but it surely matters to humanity as a whole (l. 42-44).
I - It surely matters to humanity as a whole, however it may not matter directly for everyday life.
II - Though it may not matter directly for everyday life, it surely matters to humanity as a whole.
III - Despite it may matter directly for everyday life, it surely matters to humanity as a whole.
If applied to the text, which ones would be correct and keep the original meaning?